RSL3 suppresses spheroid formation and viability, and halts migration of PTC cells in vitro We postulated that the RSL3-mediated suppression of thyroid tumor cell viability is a ferroptosis pathway-dependent process, therefore, we treated K1 cells with a lethal dose of RSL3 alone and in the presence of either a ferroptosis inhibitor Fer1, or a pan caspase inhibitor, Z-VAD-FMK (ZVAD) and measured cell viability
Lancet 372(9652):18091818 Lee SM et al (2012) First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial
Among these, a negative correlation was observed between plasma lipopolysaccharide-binding protein (LBP) levels and C4A gene copy number was observed in patients with schizophrenia, but not in healthy controls (143)
EMBO Rep 18:569585 Angel LO, Mena S, Estrela JM (2011) Glutathione in cancer cell death